Electronic Commerce (e-Commerce) and Mobile Commerce (m-Commerce) are evolving at a pace that is revolutionizing how business is carried out. These two technologies can indeed open up markets beyond borders. The purpose of this research was to propose an integrated framework for e-Commerce and m-Commerce and to suggest a suitable implementation strategy. The objectives of the research were achieved through extensive review of vast literature on the subject matters. The research starts by looking at the various aspects of Electronic Commerce and Mobile Commerce, their barriers, benefits and possible future. Existing electronic payment modes were then discussed to identify common methods in which online transactions take place. It was found that there exists a formal framework for eCommerce, but frameworks for m-Commerce were organization specific. Extensive data collection and analysis was done to ensure that the proposed framework was as close to facts on the ground as possible. Data analysis was done using Statistical Package for the Social Sciences (SPSS) 17 and Microsoft Excel 2007. Results of the analysis indicated that 51% of the population knew about e-Commerce. It also found that only 15% had used credit cards to pay for items bought online. The proposed generic framework can help provide a starting point for e-Commerce businesses in Kenya enabling them to operate on similar platform. This proposed theoretical framework borrows from the works of Turban et al., in 2006 and aside from additional components; it allows implementers focus on important aspects of eCommerce and m-Commerce that would otherwise not receive the attention that they deserve such as policy and infrastructure requirements. This framework can then be modified to meet specific business needs. Lastly, recommendations for further research in this area were made.